alpha-Chymotrypsin deacylation: temperature dependence of hydrolysis and transesterification reactions.

@article{Wang1981alphaChymotrypsinDT,
  title={alpha-Chymotrypsin deacylation: temperature dependence of hydrolysis and transesterification reactions.},
  author={C L-Albert Wang and Kim C Calvo and Marietta H. Klapper},
  journal={Biochemistry},
  year={1981},
  volume={20 5},
  pages={1401-8}
}
The hydrolysis and transesterification reactions of furoyl-chymotrypsins display nonlinear Arrhenius plots with no apparent discontinuities. Of a number of models considered, the best explanation assumes a temperature-dependent rapid equilibrium between two forms of acyl-enzyme with differing reactivities. Rate constants for the transesterification of alpha… CONTINUE READING