alpha-Adducin Gly460Trp polymorphism is associated with low renin hypertension in younger subjects in the Ohasama study.

@article{Sugimoto2002alphaAdducinGP,
  title={alpha-Adducin Gly460Trp polymorphism is associated with low renin hypertension in younger subjects in the Ohasama study.},
  author={Ken Sugimoto and Atsushi Hozawa and Tomohiro Katsuya and Mitsunobu Matsubara and Takayoshi Ohkubo and Ichiro Tsuji and Masaharu Motone and Jitsuo Higaki and Shigeru Hisamachi and Yutaka Imai and Toshio Ogihara},
  journal={Journal of hypertension},
  year={2002},
  volume={20 9},
  pages={1779-84}
}
BACKGROUND The Gly460Trp polymorphism of the alpha-adducin gene (ADD-1 ) has been examined as a candidate gene for essential hypertension with salt sensitivity in the Caucasian population. However, we failed to detect a positive association between the Gly460Trp polymorphism of ADD-1 and hypertension in a small series of Japanese subjects. OBJECTIVE To examine the precise association between the Gly460Trp polymorphism of ADD-1 and blood pressure (BP), we carried out an association study using… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 24 extracted citations

Similar Papers

Loading similar papers…