alpha(1D)-adrenoceptors cause endothelium-dependent vasodilatation in the rat mesenteric vascular bed.

Abstract

The vasodilator activity of alpha(1)-adrenoceptor agonists was tested in the rat mesenteric vascular bed (MVB), and the mechanism involved was investigated in cultured endothelial cells isolated from the bovine coronary vascular bed. In preparations preconstricted by U46619, noradrenaline and phenylephrine induced a slight relaxant effect at nanomolar… (More)

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@article{Filippi2001alpha1DadrenoceptorsCE, title={alpha(1D)-adrenoceptors cause endothelium-dependent vasodilatation in the rat mesenteric vascular bed.}, author={Sandra Filippi and Astrid Parenti and Sandra Donnini and Harris J. Granger and Alessandro Fazzini and Fabrizio Ledda}, journal={The Journal of pharmacology and experimental therapeutics}, year={2001}, volume={296 3}, pages={869-75} }