• Corpus ID: 37850245

agnesium effect on testosterone – SHBG association studied by a novel olecular chromatography approach

@inproceedings{Guillaume2009agnesiumEO,
  title={agnesium effect on testosterone – SHBG association studied by a novel olecular chromatography approach},
  author={Yves Claude Guillaume and Marie-Christine Woronoff-lemsi and Claire Andr{\'e}},
  year={2009}
}
A biochromatographic approach is developed to measure for the first time thermodynamic data and magnesium (Mg2+) effect for the binding of testosterone (TT) to sex hormone-binding globulin (SHBG) in a wide temperature range. For this, the SHBG was immobilized on a chromatographic support. It was established that this novel SHBG column was stable during an extended period of time. The affinity of TT to SHBG is high and changes slightly with the Mg2+ concentration because the number of Mg2… 

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