aPKC ι/λ: a potential target for the therapy of Hh-dependent and Smo-inhibitor-resistant advanced BCC.

@article{Lv2013aPKCA,
  title={aPKC ι/λ: a potential target for the therapy of Hh-dependent and Smo-inhibitor-resistant advanced BCC.},
  author={Xiangdong Lv and Lin Fu and Yun M. Zhao},
  journal={Acta biochimica et biophysica Sinica},
  year={2013},
  volume={45 7},
  pages={610-1}
}
Basal cell carcinoma (BCC), a skin cancer, is the most common malignancy in white people [1, 2]. Although mortality is low as BCC rarely metastasizes, people suffering from BCC are at high risk of developing other malignancies [3]. Given its low metastatic potential, treatment of BCC focuses on local control, including surgical and non-surgical measures [3, 4]. In the best hands, the 5-year cure rates of excision, curettage and cautery, and cryosurgery are 95% or higher [3]. However… CONTINUE READING

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