Zymosan induces production of superoxide anions by hemocytes of the solitary ascidian Halocynthia roretzi.

@article{Azumi2002ZymosanIP,
  title={Zymosan induces production of superoxide anions by hemocytes of the solitary ascidian Halocynthia roretzi.},
  author={Kaoru Azumi and Futoshi Kuribayashi and Shiro Kanegasaki and Hideyoshi Yokosawa},
  journal={Comparative biochemistry and physiology. Toxicology & pharmacology : CBP},
  year={2002},
  volume={133 4},
  pages={567-74}
}
Reactive oxygen intermediates (ROIs), including superoxide anions and hydrogen peroxide, are generated by phagocytes in invertebrates, as well as in vertebrates. To understand the molecular mechanisms underlying the generation of ROIs by hemocytes of the solitary ascidian Halocynthia roretzi, we established a method of measuring ROIs using luminol-dependent chemiluminescence (LDCL). LDCL analyses revealed that both zymosan and phorbol myristate acetate (PMA), but not lipopolysaccharide, beta1,3… CONTINUE READING