Zwitterionic polycarboxybetaine coating functionalized with REDV peptide to improve selectivity for endothelial cells.

@article{Ji2012ZwitterionicPC,
  title={Zwitterionic polycarboxybetaine coating functionalized with REDV peptide to improve selectivity for endothelial cells.},
  author={Ying Ji and Yu Wei and Xiangshen Liu and Jin-lei Wang and Ke‐feng Ren and Jian Ji},
  journal={Journal of biomedical materials research. Part A},
  year={2012},
  volume={100 6},
  pages={
          1387-97
        }
}
  • Ying Ji, Yu Wei, J. Ji
  • Published 1 June 2012
  • Biology, Materials Science, Chemistry
  • Journal of biomedical materials research. Part A
Surface immobilization of bioactive molecules has been a promising strategy to develop in situ endothelialization for cardiovascular implants. With the aim to construct endothelial cell specific coating with low fouling property, zwitterionic carboxybetaine methacrylate and butyl methacrylate were copolymerized as coating materials, spin-coated onto substrates, and immobilized with endothelial cell selective peptide Arg-Glu-Asp-Val (REDV) through functionalization of carboxy groups in… 
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