Zur RNA-Synthese im Verlauf der Lebercarcinogenese durch Diäthylnitrosamin

Abstract

The incorporation of 3H-cytidine (RNA synthesis) into liver explants under standardized in vitro conditions was measured during hepatocarcinogenesis by continuous oral administration of diethylnitrosamine (DENA) to adult rats. At the daily dose of 5 mg DENA per kg body weight, the median time until death with hepatocellular carcinomata was 160 days ±6%. (S… (More)
DOI: 10.1007/BF00527576

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