Zoonotic Brazilian Vaccinia virus: from field to therapy.

  title={Zoonotic Brazilian Vaccinia virus: from field to therapy.},
  author={Erna Geessien Kroon and Bruno Eduardo Fernandes Mota and J{\^o}natas Santos Abrah{\~a}o and Fl{\'a}vio Guimar{\~a}es da Fonseca and Giliane de Souza Trindade},
  journal={Antiviral research},
  volume={92 2},
Vaccinia virus (VACV), the prototype species of the Orthopoxvirus (OPV) genus, causes an occupational zoonotic disease in Brazil that is primarily associated with the handling of infected dairy cattle. Cattle and human outbreaks have been described in southeastern Brazil since 1999 and have now occurred in almost half of the territory. Phylogenetic studies have shown high levels of polymorphisms among isolated VACVs, which indicate the existence of at least two genetically divergent clades… CONTINUE READING
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