Zooming-in on cancer metabolic rewiring with tissue specific constraint-based models


The metabolic rearrangements occurring in cancer cells can be effectively investigated with a Systems Biology approach supported by metabolic network modeling. We here present tissue-specific constraint-based core models for three different types of tumors (liver, breast and lung) that serve this purpose. The core models were extracted and manually curated… (More)
DOI: 10.1016/j.compbiolchem.2016.03.002

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