Zonulin and its regulation of intestinal barrier function: the biological door to inflammation, autoimmunity, and cancer.

@article{Fasano2011ZonulinAI,
  title={Zonulin and its regulation of intestinal barrier function: the biological door to inflammation, autoimmunity, and cancer.},
  author={Alessio Fasano},
  journal={Physiological reviews},
  year={2011},
  volume={91 1},
  pages={151-75}
}
The primary functions of the gastrointestinal tract have traditionally been perceived to be limited to the digestion and absorption of nutrients and to electrolytes and water homeostasis. A more attentive analysis of the anatomic and functional arrangement of the gastrointestinal tract, however, suggests that another extremely important function of this organ is its ability to regulate the trafficking of macromolecules between the environment and the host through a barrier mechanism. Together… CONTINUE READING

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ZONULIN AND INTESTINAL BARRIER FUNCTION Physiol Rev

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