Zone-specific remodeling of tumor blood vessels affects tumor growth.

@article{Tilki2007ZonespecificRO,
  title={Zone-specific remodeling of tumor blood vessels affects tumor growth.},
  author={Derya Tilki and N. Koray Kilic and Sema Sevinc and Friedrich Zywietz and Christian G Stief and Suleyman Ergun},
  journal={Cancer},
  year={2007},
  volume={110 10},
  pages={
          2347-62
        }
}
BACKGROUND Chaotic organization, abnormal leakiness, and structural instability are characteristics of tumor vessels. However, morphologic events of vascular remodeling in relation to tumor growth are not sufficiently studied yet. METHODS By using the rat rhabdomyosarcoma tumor model vascular morphogenesis was studied by light and electron microscopy and immunohistochemistry in relation to tumor regions such as tumor surrounding (TSZ), marginal (TMZ), intermediate (TIZ), and center (TCZ… CONTINUE READING
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