Zone model predictive control: a strategy to minimize hyper- and hypoglycemic events.

@article{Grosman2010ZoneMP,
  title={Zone model predictive control: a strategy to minimize hyper- and hypoglycemic events.},
  author={Benyamin Grosman and Eyal Dassau and Howard C. Zisser and Lois Jovanovi{\vc} and Francis J. Doyle},
  journal={Journal of diabetes science and technology},
  year={2010},
  volume={4 4},
  pages={961-75}
}
BACKGROUND Development of an artificial pancreas based on an automatic closed-loop algorithm that uses a subcutaneous insulin pump and continuous glucose sensor is a goal for biomedical engineering research. However, closing the loop for the artificial pancreas still presents many challenges, including model identification and design of a control algorithm that will keep the type 1 diabetes mellitus subject in normoglycemia for the longest duration and under maximal safety considerations… CONTINUE READING