Zonal Uniformity in Mechanical Properties of the Chondrocyte Pericellular Matrix: Micropipette Aspiration of Canine Chondrons Isolated by Cartilage Homogenization

@article{Guilak2005ZonalUI,
  title={Zonal Uniformity in Mechanical Properties of the Chondrocyte Pericellular Matrix: Micropipette Aspiration of Canine Chondrons Isolated by Cartilage Homogenization},
  author={Farshid Guilak and Leonidas G. Alexopoulos and Mansoor A. Haider and H P Ting-beall and Lori A. Setton},
  journal={Annals of Biomedical Engineering},
  year={2005},
  volume={33},
  pages={1312-1318}
}
The pericellular matrix (PCM) is a region of tissue that surrounds chondrocytes in articular cartilage and together with the enclosed cells is termed the chondron. Previous studies suggest that the mechanical properties of the PCM, relative to those of the chondrocyte and the extracellular matrix (ECM), may significantly influence the stress–strain, physicochemical, and fluid-flow environments of the cell. The aim of this study was to measure the biomechanical properties of the PCM of… CONTINUE READING
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