Zolpidem for persistent vegetative state--a placebo-controlled trial in pediatrics.

  title={Zolpidem for persistent vegetative state--a placebo-controlled trial in pediatrics.},
  author={Natasha Snyman and Jonathan Egan and Kevin London and Roberts Howman-Giles and Derek Singh Gill and Jennifer E Gillis and Adam M. Scheinberg},
  volume={41 5},
OBJECTIVE The aim of this study was to determine if zolpidem is associated with improved responsiveness or regional cerebral perfusion in patients with persistent vegetative states. METHODS Following ethics approval, children with persistent vegetative state were enrolled in a prospective, double-blind, placebo-controlled randomised trial. Patients underwent 2 treatments of 4 days, separated by 10 days. Each child received either a daily dose of zolpidem or placebo with a dosage of 0.14-0.2… CONTINUE READING


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