Zoledronic acid slows down rat primary chondrosarcoma development, recurrent tumor progression after intralesional curretage and increases overall survival.

Abstract

Chondrosarcoma is a difficult musculoskeletal tumor to treat. Surgical treatment leads to severe disability, with high rates of local recurrence and life threat. No adjuvant therapy is effective in differentiated chondrosarcomas. Bisphosphonates (BPs) are a class of molecules which is effective in malignant bone diseases. The aim of the present study was to… (More)

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Cite this paper

@article{Gouin2006ZoledronicAS, title={Zoledronic acid slows down rat primary chondrosarcoma development, recurrent tumor progression after intralesional curretage and increases overall survival.}, author={F. Gouin and Benjamin Ory and François R{\'e}dini and Dominique Heymann}, journal={International journal of cancer}, year={2006}, volume={119 5}, pages={980-4} }