Zoledronic Acid for the Treatment of Children With Refractory Central Giant Cell Granuloma.


There are no approved medical therapies for the treatment of pediatric central giant cell granuloma (CGCG), a benign but potentially aggressive tumor of the jaw. Zoledronic acid (ZA), a third-generation bisphosphonate, has been used in CGCG occurring in adults. We describe 4 patients with CGCG treated with ZA, 3 of whom achieved resolution of disease up to… (More)
DOI: 10.1097/MPH.0000000000000380


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