ZnT8 autoantibody titers in type 1 diabetes patients decline rapidly after clinical onset.

@article{VaziriSani2010ZnT8AT,
  title={ZnT8 autoantibody titers in type 1 diabetes patients decline rapidly after clinical onset.},
  author={Fariba Vaziri-Sani and Shilpa A Oak and Jared Radtke and Ke Lernmark and Kristian Lynch and Carl-D Agardh and Corrado Maria Cilio and Asa L Lethagen and Eva Ortqvist and Mona Landin-Olsson and Carina T{\"o}rn and Christiane S. Hampe},
  journal={Autoimmunity},
  year={2010},
  volume={43 8},
  pages={598-606}
}
Autoantibodies to the islet-specific zinc transporter isoform 8 (ZnT8) are detected in the majority of type 1 diabetes patients prior to and at clinical diagnosis. The presence of ZnT8Ab after diagnosis has not been investigated. This study analyzed the autoantibody response to ZnT8 in regard to age at onset and disease duration. Two new onset type 1 diabetes patient cohorts with different age distributions at onset (2-17 and 15-34 years of age at onset), a longitudinal subset of the younger… CONTINUE READING