ZnT3 Gene Deletion Reduces Colchicine-Induced Dentate Granule Cell Degeneration


Our previous study demonstrated that colchicine-induced dentate granule cell death is caused by blocking axonal flow and the accumulation of intracellular zinc. Zinc is concentrated in the synaptic vesicles via zinc transporter 3 (ZnT3), which facilitates zinc transport from the cytosol into the synaptic vesicles. The aim of the present study was to… (More)
DOI: 10.3390/ijms18102189


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