Zirconium oxide regulates RNA interfering of osteoblast-like cells.

  title={Zirconium oxide regulates RNA interfering of osteoblast-like cells.},
  author={Annalisa Palmieri and Furio Pezzetti and Giorgio Brunelli and Ilaria Zollino and Lorenzo Lo Muzio and Marcella Martinelli and Luca Scapoli and Marzia Arlotti and Elena Masiero and Francesco Carinci},
  journal={Journal of materials science. Materials in medicine},
  volume={19 6},
Zirconium oxide (ZO) has outstanding mechanical properties, high biocompatibility and high resistance to scratching. Since dental implants are made with ZO and the genetic effects of ZO on osteoblasts are incompletely understood, we used microRNA microarray techniques to investigate the translation process in osteoblasts exposed to ZO. By using miRNA microarrays containing 329 probes designed from Human miRNA sequences, we identified in osteoblast-like cells line (MG-63) cultured on ZO disks… CONTINUE READING