Zingiber officinale Roscoe prevents acetaminophen-induced acute hepatotoxicity by enhancing hepatic antioxidant status.

@article{Ajith2007ZingiberOR,
  title={Zingiber officinale Roscoe prevents acetaminophen-induced acute hepatotoxicity by enhancing hepatic antioxidant status.},
  author={Thekkoottuparambil Ananthanarayanan Ajith and Unnikrishnan Hema and M. S. Aswathy},
  journal={Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association},
  year={2007},
  volume={45 11},
  pages={2267-72}
}
A large number of xenobiotics are reported to be potentially hepatotoxic. Free radicals generated from the xenobiotic metabolism can induce lesions of the liver and react with the basic cellular constituents - proteins, lipids, RNA and DNA. Hepatoprotective activity of aqueous ethanol extract of Zingiber officinale was evaluated against single dose of acetaminophen-induced (3g/kg, p.o.) acute hepatotoxicity in rat. Aqueous extract of Z. officinale significantly protected the hepatotoxicity as… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 65 extracted citations

A critical review on hepatoprotective effects of bioactive food components.

Critical reviews in food science and nutrition • 2018
View 4 Excerpts
Highly Influenced

Effect of S-methylisothiourea in acetaminophen-induced hepatotoxicity in rat

Naunyn-Schmiedeberg's Archives of Pharmacology • 2012
View 2 Excerpts
Highly Influenced

Of Carbon Tetrachloride-induced Rat Liver Injury by Ginger Extract ( Zingiber Officinale )

E RESEARCHARTICL, Dalia FA. Abou-Zaid
2009
View 3 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…