Zinc suppresses stem cell properties of lung cancer cells through protein kinase C-mediated β-catenin degradation.

Abstract

Highly tumorigenic cancer stem cells (CSCs) residing in most cancers are responsible for cancer progression and treatment failure. Zinc is an element regulator of several cell functions; however, its role in regulation of stem cell program in lung cancer has not been demonstrated. The present study reveals for the first time that zinc can suppress stem cell… (More)
DOI: 10.1152/ajpcell.00173.2016

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