Zinc supplementation attenuates insulin secretory activity in pancreatic islets of the ob/ob mouse.

@article{BginHeick1985ZincSA,
  title={Zinc supplementation attenuates insulin secretory activity in pancreatic islets of the ob/ob mouse.},
  author={Nicole B{\'e}gin-Heick and Marthe Dalp{\'e}-Scott and Janet Rowe and Hans M. C. Heick},
  journal={Diabetes},
  year={1985},
  volume={34 2},
  pages={179-84}
}
The purpose of this study was to establish whether a relationship may exist between the hyperinsulinemia, the exaggerated insulin secretion, and the resistance to insulin characteristic of the obese-hyperglycemic syndrome and the zinc status of the ob/ob mouse. To this end, mice were given control and zinc-supplemented diets, and the effects of zinc supplementation on insulin secretion in vivo and in vitro as well as on glucose tolerance were studied. These data were compared with those… CONTINUE READING

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