Zinc protoporphyrin, zinc ion, and protoporphyrin reduce focal cerebral ischemia.

@article{Zhao1996ZincPZ,
  title={Zinc protoporphyrin, zinc ion, and protoporphyrin reduce focal cerebral ischemia.},
  author={Yang Zhao and Guo-Yuan Yang and Edward F. Domino},
  journal={Stroke},
  year={1996},
  volume={27 12},
  pages={2299-303}
}
BACKGROUND AND PURPOSE Zinc protoporphyrin pretreatment protects against temporary focal ischemic brain injury in rats. However, it is not known whether the zinc or the protoporphyrin portion of zinc protoporphyrin has effects on focal cerebral ischemia. Hence, all three agents were compared with regard to infarct size and edema in a rat model of middle cerebral artery occlusion. METHODS Four groups of adult male Sprague-Dawley rats were subjected to 2 hours of temporary middle cerebral… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

Similar Papers

Loading similar papers…