Zinc finger protein Zn72D promotes productive splicing of the maleless transcript.

@article{Worringer2007ZincFP,
  title={Zinc finger protein Zn72D promotes productive splicing of the maleless transcript.},
  author={Kathleen A. Worringer and Barbara Panning},
  journal={Molecular and cellular biology},
  year={2007},
  volume={27 24},
  pages={8760-9}
}
In organisms with sex chromosomes, dosage compensation equalizes gene expression between the sexes. In Drosophila melanogaster males, the male-specific lethal (MSL) complex of proteins and two noncoding roX RNAs coat the X chromosome, resulting in a twofold transcriptional upregulation to equalize gene expression with that of females. How MSL complex enrichment on the X chromosome is regulated is not well understood. We performed an RNA interference screen to identify new factors required for… CONTINUE READING