Zinc finger domains: hypotheses and current knowledge.

  • Jamee M. Berg
  • Published 1990 in
    Annual review of biophysics and biophysical…


Many of the hypotheses are clearly correct that are based on the initial observation that TFIIIA has an approximately periodic structure with invariant pairs of cysteines and histidines apparently capable of coordinating metal ions. A startling number of other cDNA clones encode proteins that contain one or more sequences that match the zinc finger… (More)


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