Zinc deficiency mediates alcohol-induced alveolar epithelial and macrophage dysfunction in rats.

Abstract

Chronic alcohol abuse impairs both alveolar epithelial and macrophage function, and renders individuals susceptible to acute lung injury, pneumonia, and other serious lung diseases. Zinc deficiency, which is known to impact both epithelial and immune cell functions, is also associated with alcohol abuse. In this study, chronic alcohol ingestion (6 wk) in… (More)
DOI: 10.1165/rcmb.2008-0209OC

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