Zinc Transporter 8 Antibodies Complement GAD and IA-2 Antibodies in the Identification and Characterization of Adult-Onset Autoimmune Diabetes

@inproceedings{Lampasona2010ZincT8,
  title={Zinc Transporter 8 Antibodies Complement GAD and IA-2 Antibodies in the Identification and Characterization of Adult-Onset Autoimmune Diabetes},
  author={Vito Lampasona and Antonio Petrone and Claudio Tiberti and Marco Capizzi and Marialuisa Spoletini and Sergio di Pietro and Marco Songini and Sara Bonicchio and Francesco Giorgino and Ezio Bonifacio and Emanuele Bosi and Raffaella Buzzetti},
  booktitle={Diabetes care},
  year={2010}
}
OBJECTIVE Zinc transporter 8 (ZnT8) is an islet beta-cell secretory granule membrane protein recently identified as an autoantibody antigen in type 1 diabetes. The aim of this study was to determine the prevalence and role of antibodies to ZnT8 (ZnT8As) in adult-onset diabetes. RESEARCH DESIGN AND METHODS ZnT8As were measured by a radioimmunoprecipitation assay using recombinant ZnT8 COOH-terminal or NH(2)-terminal proteins in 193 patients with adult-onset autoimmune diabetes having… CONTINUE READING
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