Zinc Deficiency and Taste Disorders

@article{Heyneman1996ZincDA,
  title={Zinc Deficiency and Taste Disorders},
  author={Catherine A. Heyneman},
  journal={Annals of Pharmacotherapy},
  year={1996},
  volume={30},
  pages={186 - 187}
}
  • C. Heyneman
  • Published 1 February 1996
  • Medicine
  • Annals of Pharmacotherapy
Elemental zinc supplementation in daily dosages of 25-100 mg po appears to be an efficacious treatment for taste dysfunction secondary to zinc depletion. Insufficient evidence is available to determine the efficacy of zinc supplementation for the treatment of hypogeusia or dysgeusia secondary to drug therapy or medical conditions that do not involve low serum zinc concentrations. 

Topics from this paper

Zinc: pathophysiologic effects, nutritional deficiency, and effects of supplementation in older people — a review
TLDR
This paper will briefly review the pathophysicologic effects of zinc, nutritional deficiency, and effect of zinc supplementation in older people. Expand
Zinc: An overview and therapeutic uses in dermatology
Zinc is an essential component of various important enzymes in our body and its deficiency causes multi-enzyme defects and multisystemic disease. It ranks with biotin as a truly essential element inExpand
Effects of zinc supplementation on serum zinc concentration and ratio of apo/holo-activities of angiotensin converting enzyme in patients with taste impairment.
TLDR
It is indicated that zinc deficiency is a predominant factor underlying taste impairment and ACE ratio may be a predictor of the prognosis for taste impairment after zinc supplementation, in addition to a more sensitive indicator of zinc nutrition than zinc concentration in the serum. Expand
Ensuring Adequate Zinc Status in Vegans
Zinc is an essential mineral that is naturally present in some foods, added to others, and available as a dietary supplement. It is involved in numerous aspects of cellular metabolism, and alsoExpand
A Case Series: Zinc Deficiency as a Potential Contributor to Oral Dysgeusia
  • G. Guan
  • Medicine
  • Modern Approaches in Dentistry and Oral Health Care
  • 2018
TLDR
Several studies have suggested that oral dysgeusia may be one of the important symptoms of zinc deficiency, and zinc deficiency is an important trace element for many biochemical functions. Expand
A zinc-containing compound, Polaprezinc, is effective for patients with taste disorders: randomized, double-blind, placebo-controlled, multi-center study
Conclusions. The effect of a zinc-containing compound, Polaprezinc, was shown to clinically improve the disease conditions of idiopathic taste disorders with no serious side effects in a wellExpand
Reliability of the AccuSens Taste Kit© in patients with eating disorders
TLDR
The taste test, the only commercially available taste test for zinc deficiency, was found to be unreliable and should not be used to determine zinc status. Expand
Zinc deficiency and its management in the pediatric population: a literature review and proposed etiologic classification.
TLDR
The aim of this review is to focus on the cutaneous manifestations, diagnosis, and treatment of zinc deficiency in children, and to propose an etiologic classification system. Expand
Need of education and awareness towards zinc supplementation: A review
TLDR
The need of health education and awareness programmes for effective zinc supplementation is highlighted. Expand
Zinc Gluconate in the Treatment of Dysgeusia—a Randomized Clinical Trial
TLDR
In conclusion, zinc appears to improve general gustatory function and, consequently, general mood scores in dysgeusia patients. Expand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 19 REFERENCES
Improvement of uremic hypogeusia by zinc: a double-blind study.
TLDR
Uremic hypogeusia improved in association with zinc supplementation and elevation of plasma zinc concentration and the threshold of taste detection and recognition for salt, sweet, and bitter but not for sour improved significantly in patients on zinc supplementation. Expand
A double blind study of the effects of zinc sulfate on taste and smell dysfunction
TLDR
Although results demonstrate abnormalities of zinc metabolism in some patients with taste and smell dysfunction they fail to provide evidence for a single, therapeutic approach to the many disorders which are associated with abnormalities of taste and sense, the methods and procedures developed demonstrate that taste and taste dysfunction can be studied in a quantitative, systematic manner. Expand
Zinc metabolism in renal failure.
TLDR
Manifestations of zinc deficiency include abnormal bone metabolism, skin lesions, testicular atrophy, and impaired wound healing and are also common in uremia. Expand
A double-blind study of the therapeutic efficacy of zinc gluconate on taste disorder.
TLDR
A significant superiority of zinc gluconate to placebo was observed in patients with idiopathic and zinc-deficient taste disorder and a significant difference was detected between the two groups in overall efficacy. Expand
Hypocupremia induced by zinc therapy in adults.
TLDR
Hypocupremia occurred in an adult with sickle cell anemia who received zinc as an antisickling agent for two years and was associated with microcytosis and relative neutropenia, which was easily corrected by copper supplementation. Expand
Zinc deficiency: a reversible complication of uremia.
TLDR
Improvements in biochemical as well as clinical parameters confirm and extend earlier observations of improvement in taste and sexual function after zinc supplementation, and suggest that zinc deficiency is a complicating feature of uremia and can be corrected by oral zinc supplementation. Expand
Zinc deficiency in elderly patients.
TLDR
Improvement in response to skin-test antigens and taste acuity was observed after zinc supplementation, and a mild zinc deficiency appears to be a significant clinical problem in free-living elderly people. Expand
Disorders of taste.
  • E. Rareshide, R. Amedee
  • Medicine
  • The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society
  • 1989
TLDR
Evaluation consists of a history and physical, followed by a screening test battery searching for any of the treatable etiologies, and one third of patients will respond to exogenous zinc therapy after a treatment period of 2 to 4 months. Expand
Taste and smell in disease.
TLDR
Chronic disorders of taste and smell have been largely neglected because they are seldom fatal and, unlike deficiencies in sight or hearing, are not considered serious handicaps. Expand
Decreased NaCl sensitivity in zinc-deprived rats
TLDR
It is demonstrated that zinc deprivation induces decreased gustatory sensitivity and a role for zinc in taste is confirmed and confirmed and revealed in pair-fed controls maintained on supplemental zinc. Expand
...
1
2
...