Zika Virus and Microcephaly.

  title={Zika Virus and Microcephaly.},
  author={Eric J. Rubin and Michael F. Greene and Lindsey Robert Baden},
  journal={The New England journal of medicine},
  volume={374 10},
Zika virus has been sweeping through South and Central America, with more than a million suspected cases during the past few months, along with a substantial increase in reporting of infants born with microcephaly.1,2 Thus far, the two outbreaks have largely been epidemiologically associated in time and geography. However, Mlakar and colleagues3 now report in the Journal molecular genetic and electron-microscopic data from a case that helps to strengthen the biologic association. This group… 

Accidental discovery and isolation of Zika virus in Uganda and the relentless epidemiologist behind the investigations

The purpose of this manuscript is to review the very early research that led to the discovery and partial characterization of the virus along with some current thoughts and add few personal anecdotes about the scientist who discovered it.

An overview of the current medical literature on Zika virus.

  • F. Hossein
  • Medicine, Biology
    Biophysical reviews
  • 2020
An update on the status of the Zika outbreak is provided, including a description of available medical countermeasure options and current diagnosis methodology, and antigenic similarities between Zika and dengue can suggest artificially high infection rates of Zika within specific population groups.

Challenger Treats Zika Virus

It is concluded that some of these compounds testing in vitro and in vivo have shown a therapeutic possibilities to consider and to be test in pregnancy and in individuals with high risk of infection.

Zika virus in French Polynesia 2013-14: anatomy of a completed outbreak.

Revista Colombiana de Anestesiología

The ZIKVgenome consists of an RNA molecule thatencodes for a polyprotein which, following processing, results in the production of three structural proteins (C, prM and E) and seven non-structural proteins (NS).



Zika Virus Associated with Microcephaly.

The case of an expectant mother who had a febrile illness with rash at the end of the first trimester of pregnancy while she was living in Brazil and revealed microcephaly with calcifications in the fetal brain and placenta is described.

Possible Association Between Zika Virus Infection and Microcephaly - Brazil, 2015.

Pregnant women in Zika virus-affected areas should protect themselves from mosquito bites by using air conditioning, screens, or nets when indoors, wearing long sleeves and pants, using permethrin-treated clothing and gear, and using insect repellents when outdoors.

Zika virus intrauterine infection causes fetal brain abnormality and microcephaly: tip of the iceberg?

Examination of two pregnant women from the state of Paraiba who were diagnosed with fetal microcephaly and were considered part of the ‘microCEphaly cluster’ was positive for Zika virus in both patients, most likely representing the first diagnoses of intrauterine transmission of the virus.

Zika Virus in the Americas--Yet Another Arbovirus Threat.

The explosive pandemic of Zika virus infection in South and Central America is the most recent of four unexpected arrivals of important arthropod-borne viral diseases in the Western Hemisphere over

Zika virus outbreak on Yap Island, Federated States of Micronesia.

This outbreak of Zika virus illness in Micronesia represents transmission of Zikairus outside Africa and Asia and clinicians and public health officials should be aware of the risk of further expansion of Zika viruses transmission.

The Neglected Dimension of Global Security--A Framework for Countering Infectious-Disease Crises.

An international expert group has outlined a framework for preparedness, detection, and response to future infectious-disease threats.

Possible association between Zika virus infection and microcephaly — Brazil ,

  • MMWR Morb Mortal Wkly Rep
  • 2015

Uber bakteriologische Forschung Verhand - lung des X Internationalen Medichinischen Congresses , Berlin , 1890 , 1 , 35

  • 1891