Zika Virus and Birth Defects--Reviewing the Evidence for Causality.

  title={Zika Virus and Birth Defects--Reviewing the Evidence for Causality.},
  author={Sonja A. Rasmussen and Denise J. Jamieson and Margaret A. Honein and Lyle R. Petersen},
  journal={The New England journal of medicine},
  volume={374 20},
Summary The Zika virus has spread rapidly in the Americas since its first identification in Brazil in early 2015. Prenatal Zika virus infection has been linked to adverse pregnancy and birth outcomes, most notably microcephaly and other serious brain anomalies. To determine whether Zika virus infection during pregnancy causes these adverse outcomes, we evaluated available data using criteria that have been proposed for the assessment of potential teratogens. On the basis of this review, we… 

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