Zika Virus and Birth Defects--Reviewing the Evidence for Causality.

  title={Zika Virus and Birth Defects--Reviewing the Evidence for Causality.},
  author={S. Rasmussen and D. Jamieson and M. Honein and L. Petersen},
  journal={The New England journal of medicine},
  volume={374 20},
  • S. Rasmussen, D. Jamieson, +1 author L. Petersen
  • Published 2016
  • Medicine
  • The New England journal of medicine
  • Summary The Zika virus has spread rapidly in the Americas since its first identification in Brazil in early 2015. Prenatal Zika virus infection has been linked to adverse pregnancy and birth outcomes, most notably microcephaly and other serious brain anomalies. To determine whether Zika virus infection during pregnancy causes these adverse outcomes, we evaluated available data using criteria that have been proposed for the assessment of potential teratogens. On the basis of this review, we… CONTINUE READING
    1,335 Citations

    Tables and Topics from this paper.

    Zika virus infection and pregnancy: what we do and do not know
    • 21
    Teratogen update: Zika virus and pregnancy
    Characterizing the Pattern of Anomalies in Congenital Zika Syndrome for Pediatric Clinicians
    • 432
    • PDF
    Zika Virus Infection in Pregnancy: Maternal, Fetal, and Neonatal Considerations
    • 25
    • Highly Influenced
    • PDF
    Emerging Role of Zika Virus in Adverse Fetal and Neonatal Outcomes
    • 113
    • Highly Influenced
    • PDF
    Possible Zika Virus Infection Among Pregnant Women - United States and Territories, May 2016.
    • 36
    • PDF


    Possible Association Between Zika Virus Infection and Microcephaly - Brazil, 2015.
    • 756
    • PDF
    Zika virus intrauterine infection causes fetal brain abnormality and microcephaly: tip of the iceberg?
    • 602
    • PDF
    Zika Virus Associated with Microcephaly.
    • 1,857
    • PDF
    Zika Virus Infection in Pregnant Women in Rio de Janeiro.
    • 1,188
    • PDF
    Initial Description of the Presumed Congenital Zika Syndrome.
    • 193
    Zika Virus Infection Among U.S. Pregnant Travelers - August 2015-February 2016.
    • 86
    • PDF
    Detection and sequencing of Zika virus from amniotic fluid of fetuses with microcephaly in Brazil: a case study.
    • 842
    • PDF