Zidovudine-associated adverse reactions in a longitudinal study of asymptomatic HIV-1-infected homosexual males.

@article{Baum1991ZidovudineassociatedAR,
  title={Zidovudine-associated adverse reactions in a longitudinal study of asymptomatic HIV-1-infected homosexual males.},
  author={Marianna K. Baum and J J Javier and Emilio Mantero-Atienza and Robert Beach and Mary Ann Fletcher and Howerde E. Sauberlich and Daniel Feaster and Gail Shor-Posner},
  journal={Journal of acquired immune deficiency syndromes},
  year={1991},
  volume={4 12},
  pages={1218-26}
}
Chemotherapeutic regimens frequently interact with and may influence nutritional factors. To determine the possible effects of zidovudine (ZDV) treatment on nutrient status, this study examined and compared the nutritional, immunological, and hematological status of asymptomatic, CDC stage III, HIV-1-seropositive males (n = 15) provided with ZDV (500-1,200 mg/day) and 22 nontreated, CD4-matched HIV-1-seropositive subjects. Prior to ZDV administration, hematological and plasma nutrient levels… CONTINUE READING