Ziconotide for treatment of severe chronic pain

  title={Ziconotide for treatment of severe chronic pain},
  author={A. Schmidtko and J. L{\"o}tsch and R. Freynhagen and G. Geisslinger},
  journal={The Lancet},
  • A. Schmidtko, J. Lötsch, +1 author G. Geisslinger
  • Published 2010
  • Medicine
  • The Lancet
  • Pharmacological management of severe chronic pain is difficult to achieve with currently available analgesic drugs, and remains a large unmet therapeutic need. The synthetic peptide ziconotide has been approved by the US Food and Drug Administration and the European Medicines Agency for intrathecal treatment of patients with severe chronic pain that is refractory to other treatment modalities. Ziconotide is the first member in the new drug class of selective N-type voltage-sensitive calcium… CONTINUE READING
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