Corpus ID: 39654917

Zerumbone induces G 1 cell cycle arrest and apoptosis in cervical carcinoma cells

  title={Zerumbone induces G 1 cell cycle arrest and apoptosis in cervical carcinoma cells},
  author={Yuzhen Zhou and Wei Tu and Chang Shu and Xiaojie Gu and Yan Huang and Xiao Shen and Hongqing Gu},
Cervical carcinoma is a cancer arising from the cervix, and it is the fourth most common cause of death in women. However, currently the candidate drugs to suppress cervical carcinoma remain lacking. This research was carried out to investigate if zerumbone, a natural cyclic sesquiterpene isolated from Zingiber zerumbet Smith, will produce the anticancer effects on cervical carcinoma cell lines. We demonstrated here for the first time that zerumbone significantly suppressed the viability of… Expand

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