Corpus ID: 52207723

Zerumbone Exerts Antiproliferative Activity via Apoptosis on HepG2 Cells

@inproceedings{Alwi2007ZerumboneEA,
  title={Zerumbone Exerts Antiproliferative Activity via Apoptosis on HepG2 Cells},
  author={Sharifah Sakinah Syed Alwi and Meenakshii Nallappan and Azimahtol Hawariah Lope Pihie},
  year={2007}
}
Zerumbone, a cytotoxic component isolated from Zingiber zerumbet Smith, significantly displayed antiproliferative effect towards human cancer cell lines including the human liver cancer HepG2 cell line (IC50 of 3.45 ± 0.026 ∝g/ml), human breast cancer MCF7 cell line (IC50 of 3.73 ± 0.085 ∝g/ml), human ovarian cancer Caov-3 cell line (IC50 of 4.73 ± 0.052 ∝g/ml) and human cervix cancer HeLa cell line (IC50 of 5.43 ± 0.033 ∝g/ml). The action of zerumbone appeared to be cytoselective as its effect… Expand

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