Zero-order delivery with periodontal placement of tetracycline-loaded ethylene vinyl acetate fibers.

@article{Tonetti1990ZeroorderDW,
  title={Zero-order delivery with periodontal placement of tetracycline-loaded ethylene vinyl acetate fibers.},
  author={Maurizio S Tonetti and Maryann Cugini and J Max Goodson},
  journal={Journal of periodontal research},
  year={1990},
  volume={25 4},
  pages={243-9}
}
The concentration of tetracycline in the gingival fluid was measured in the periodontal pocket following placement of controlled drug delivery monolithic fibers and subgingival irrigation. Following subgingival irrigation with 1% and 10% tetracycline HCl solution, concentrations decayed exponentially with half times of 4.2 and 12.2 h, respectively. Tetracycline fibers maintained a constant average concentration of 1590 micrograms/ml in periodontal pockets over a 10-day period. The observed… CONTINUE READING
19 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 19 extracted citations

Similar Papers

Loading similar papers…