Zero length conformation-dependent cross-linking of phosphorylase kinase subunits by transglutaminase.


Transglutaminase, a zero length cross-linker that catalyzes the formation of isopeptide bonds between proximal Gln and Lys side chains, was used as a structural and conformational probe of the hexadecameric phosphorylase kinase molecule (alpha beta gamma delta)4. Brief cross-linking of nonactivated kinase caused formation of alpha-beta dimers, with no cross… (More)


Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.