Zein microspheres as drug/antigen carriers: a study of their degradation and erosion, in the presence and absence of enzymes.

@article{HurtadoLpez2006ZeinMA,
  title={Zein microspheres as drug/antigen carriers: a study of their degradation and erosion, in the presence and absence of enzymes.},
  author={Pepi Hurtado-L{\'o}pez and Sudax Murdan},
  journal={Journal of microencapsulation},
  year={2006},
  volume={23 3},
  pages={303-14}
}
In the laboratory, zein microspheres are being investigated as drug/vaccine delivery systems. Preliminary experiments revealed that the release of an entrapped solute (ovalbumin, a model antigen) was limited when particles were incubated in phosphate buffered saline over a number of days. To understand the slow and limited release of the guest molecule and predict microsphere fate in vivo, the degradation of zein microspheres in different media, in the presence and in the absence of enzymes… CONTINUE READING

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