Zebrin II immunoreactivity in the rat and in the weakly electric teleost Eigenmannia (gymnotiformes) reveals three modes of Purkinje cell development.

@article{Lannoo1991ZebrinII,
  title={Zebrin II immunoreactivity in the rat and in the weakly electric teleost Eigenmannia (gymnotiformes) reveals three modes of Purkinje cell development.},
  author={Michael J. Lannoo and G. Brochu and Leonard Maler and Richard Hawkes},
  journal={The Journal of comparative neurology},
  year={1991},
  volume={310 2},
  pages={215-33}
}
Monoclonal antibody (mab) anti-zebrin II recognizes a single 36-kD polypeptide in Purkinje cells in the rat and fish cerebellum. In the adult rat, zebrin II+ Purkinje cells form, in each hemicerebellum, seven parasagittal bands interposed by zebrin II- bands. We show that, in rats, immunoreactivity first appears caudally at postnatal day 5 and spreads; all Purkinje cells are labelled by postnatal day 12. Subsequently, immunoreactivity is selectively lost so that by day 18 the adult pattern of… CONTINUE READING

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