Zebrafish sin3b mutants are viable but have size, skeletal, and locomotor defects.


BACKGROUND The transcriptional co-repressor Sin3 is highly conserved from yeast to vertebrates and has multiple roles controlling cell fate, cell cycle progression, and senescence programming. Sin3 proteins recruit histone deacetylases and other chromatin modifying factors to specific loci through interactions with transcription factors including Myc, Rest… (More)
DOI: 10.1002/dvdy.24581


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