Zebrafish regenerate full thickness optic nerve myelin after demyelination, but this fails with increasing age

@inproceedings{Mnzel2014ZebrafishRF,
  title={Zebrafish regenerate full thickness optic nerve myelin after demyelination, but this fails with increasing age},
  author={Eva Jolanda M{\"u}nzel and Catherina G. Becker and Thilo Becker and Anna W. Williams},
  booktitle={Acta neuropathologica communications},
  year={2014}
}
INTRODUCTION In the human demyelinating central nervous system (CNS) disease multiple sclerosis, remyelination promotes recovery and limits neurodegeneration, but this is inefficient and always ultimately fails. Furthermore, these regenerated myelin sheaths are thinner and shorter than the original, leaving the underlying axons potentially vulnerable. In rodent models, CNS remyelination is more efficient, so that in young animals (but not old) the number of myelinated axons is efficiently… CONTINUE READING

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