Zebrafish narrowminded suggests a genetic link between formation of neural crest and primary sensory neurons.

@article{Artinger1999ZebrafishNS,
  title={Zebrafish narrowminded suggests a genetic link between formation of neural crest and primary sensory neurons.},
  author={Kristin Bruk Artinger and Ajay B. Chitnis and M. Mercola and Wolfgang Driever},
  journal={Development},
  year={1999},
  volume={126 18},
  pages={3969-79}
}
In the developing vertebrate nervous system, both neural crest and sensory neurons form at the boundary between non-neural ectoderm and the neural plate. From an in situ hybridization based expression analysis screen, we have identified a novel zebrafish mutation, narrowminded (nrd), which reduces the number of early neural crest cells and eliminates Rohon-Beard (RB) sensory neurons. Mosaic analysis has shown that the mutation acts cell autonomously suggesting that nrd is involved in either the… CONTINUE READING
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