Zebrafish fgf24 functions with fgf8 to promote posterior mesodermal development.

@article{Draper2003ZebrafishFF,
  title={Zebrafish fgf24 functions with fgf8 to promote posterior mesodermal development.},
  author={Bruce W Draper and David W. Stock and Charles B Kimmel},
  journal={Development},
  year={2003},
  volume={130 19},
  pages={
          4639-54
        }
}
Fibroblast growth factor (Fgf) signaling plays an important role during development of posterior mesoderm in vertebrate embryos. Blocking Fgf signaling by expressing a dominant-negative Fgf receptor inhibits posterior mesoderm development. In mice, Fgf8 appears to be the principal ligand required for mesodermal development, as mouse Fgf8 mutants do not form mesoderm. In zebrafish, Fgf8 is encoded by the acerebellar locus, and, similar to its mouse otholog, is expressed in early mesodermal… CONTINUE READING

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