Zebrafish embryo as a tool to study tumor/endothelial cell cross-talk.

  title={Zebrafish embryo as a tool to study tumor/endothelial cell cross-talk.},
  author={Chiara Tobia and Giuseppina Gariano and Giulia De Sena and Marco Presta},
  journal={Biochimica et biophysica acta},
  volume={1832 9},
Tumor/endothelial cell cross-talk plays a pivotal role in the growth, neovascularization and metastatic dissemination of human cancer. Recent observations have shown that the teleost zebrafish (Danio rerio) may represent a powerful experimental platform in cancer research. Various tumor models have been established in zebrafish adults, juveniles, and embryos and novel genetic tools and high resolution in vivo imaging techniques have been exploited. In particular, grafting of mammalian tumor… CONTINUE READING


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