Zebrafish eleutheroembryos provide a suitable vertebrate model for screening chemicals that impair thyroid hormone synthesis.

@article{Thienpont2011ZebrafishEP,
  title={Zebrafish eleutheroembryos provide a suitable vertebrate model for screening chemicals that impair thyroid hormone synthesis.},
  author={Benedicte Thienpont and Ang{\`e}le Tingaud-Sequeira and Eva Prats and Carlos Barata and Patrick J. Babin and Demetrio Rald{\'u}a},
  journal={Environmental science & technology},
  year={2011},
  volume={45 17},
  pages={7525-32}
}
Thyroxine-immunofluorescence quantitative disruption test (TIQDT) was designed to provide a simple, rapid, alternative bioassay for assessing the potential of chemical pollutants and drugs to disrupt thyroid gland function. This study demonstrated that zebrafish eleutheroembryos provided a suitable vertebrate model, not only for screening the potential thyroid disrupting effect of molecules, but also for estimating the potential hazards associated with exposure to chemicals directly impairing… CONTINUE READING
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