Zebrafish as tools for drug discovery

  title={Zebrafish as tools for drug discovery},
  author={Calum A. Macrae and Randall T. Peterson},
  journal={Nature Reviews Drug Discovery},
The zebrafish has become a prominent vertebrate model for disease and has already contributed to several examples of successful phenotype-based drug discovery. For the zebrafish to become useful in drug development more broadly, key hurdles must be overcome, including a more comprehensive elucidation of the similarities and differences between human and zebrafish biology. Recent studies have begun to establish the capabilities and limitations of zebrafish for disease modelling, drug screening… 
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