Zebrafish as tools for drug discovery

@article{Macrae2015ZebrafishAT,
  title={Zebrafish as tools for drug discovery},
  author={C. Macrae and R. Peterson},
  journal={Nature Reviews Drug Discovery},
  year={2015},
  volume={14},
  pages={721-731}
}
The zebrafish has become a prominent vertebrate model for disease and has already contributed to several examples of successful phenotype-based drug discovery. For the zebrafish to become useful in drug development more broadly, key hurdles must be overcome, including a more comprehensive elucidation of the similarities and differences between human and zebrafish biology. Recent studies have begun to establish the capabilities and limitations of zebrafish for disease modelling, drug screening… Expand
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