Zebrafish as an experimental model: strategies for developmental and molecular neurobiology studies.

@article{Key2003ZebrafishAA,
  title={Zebrafish as an experimental model: strategies for developmental and molecular neurobiology studies.},
  author={B Key and Christine A. Devine},
  journal={Methods in cell science : an official journal of the Society for In Vitro Biology},
  year={2003},
  volume={25 1-2},
  pages={1-6}
}
Zebrafish provide a rapid and effective means for assessing gene function in the vertebrate nervous system. By employing gain- and loss-of-function techniques it is possible to obtain insights into the roles of both wild-type and heterologously expressed genes. Such approaches enable rapid progression from gene discovery to gene expression and finally to gene function even when examining development of a tissue as complex as the nervous system. Exploiting the full potential of zebrafish as a… CONTINUE READING

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A lossoffunction mutation in the CFC domain of TDGF 1 is associated with human forebrain defects

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