Zebrafish as an alternative model for hypoxic-ischemic brain damage.

@article{Yu2011ZebrafishAA,
  title={Zebrafish as an alternative model for hypoxic-ischemic brain damage.},
  author={Xinge Yu and Yang Li},
  journal={International journal of physiology, pathophysiology and pharmacology},
  year={2011},
  volume={3 2},
  pages={
          88-96
        }
}
Acute cerebral ischemia is one of the leading causes of mortality and chronic disability. Animal models provide an essential tool for understanding the complex cellular and molecular pathophysiology of hypoxic-ischemia and for testing novel neuroprotective drugs in the pre-clinical setting. In this study we tested zebrafish as a novel model for hypoxic-ischemic brain damage. We built an air-proof chamber where water inside had a low oxygen concentration (0.6-0.8 mg/L) proximate to complete… CONTINUE READING

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Zebrafish models of cerebrovascular disease

  • Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
  • 2014

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