Zebrafish: a complete animal model for in vivo drug discovery and development.
@article{Chakraborty2009ZebrafishAC, title={Zebrafish: a complete animal model for in vivo drug discovery and development.}, author={C. Chakraborty and C. Hsu and Z. Wen and C. S. Lin and G. Agoramoorthy}, journal={Current drug metabolism}, year={2009}, volume={10 2}, pages={ 116-24 } }
In last few years, the use of zebrafish (Danio rerio) in scientific research is growing very rapidly. Initially, it was a popular as a model of vertebrate development because zebrafish embryos are transparent and also develop rapidly. Presently, the research using zebrafish is expanding into other areas such as pharmacology, clinical research as a diseases model and interestingly in drug discovery. The use of zebrafish in pharmaceutical research and discovery and drug development is mainly… Expand
212 Citations
The developing zebrafish (Danio rerio): a vertebrate model for high-throughput screening of chemical libraries.
- Biology, Medicine
- Birth defects research. Part C, Embryo today : reviews
- 2011
- 96
Zebrafish models for assessing developmental and reproductive toxicity.
- Biology, Medicine
- Neurotoxicology and teratology
- 2014
- 87
- PDF
Screening drugs for myocardial disease in vivo with zebrafish: an expert update
- Medicine
- Expert opinion on drug discovery
- 2019
- 2
- PDF
Zebrafish: A Model for the Study of Toxicants Affecting Muscle Development and Function
- Biology, Medicine
- International journal of molecular sciences
- 2016
- 28
- PDF
Zebrafish Models of Neurodevelopmental Disorders: Limitations and Benefits of Current Tools and Techniques
- Biology, Medicine
- International journal of molecular sciences
- 2019
- 14
- PDF
A larval zebrafish model of bipolar disorder as a screening platform for neuro-therapeutics
- Psychology, Medicine
- Behavioural Brain Research
- 2012
- 36
References
SHOWING 1-10 OF 120 REFERENCES
Zebrafish: a preclinical model for drug screening.
- Biology, Medicine
- Assay and drug development technologies
- 2002
- 334
Zebrafish assays for drug toxicity screening
- Medicine, Biology
- Expert opinion on drug metabolism & toxicology
- 2006
- 246
The zebrafish model: use in studying cellular mechanisms for a spectrum of clinical disease entities.
- Biology, Medicine
- Current neurovascular research
- 2007
- 75
- PDF
Zebrafish: from disease modeling to drug discovery.
- Medicine, Biology
- Current opinion in drug discovery & development
- 2003
- 219
- PDF
Chemical discovery and global gene expression analysis in zebrafish
- Biology, Medicine
- Nature Biotechnology
- 2003
- 136
- PDF
The State of the Art of the Zebrafish Model for Toxicology and Toxicologic Pathology Research—Advantages and Current Limitations
- Biology, Medicine
- Toxicologic pathology
- 2003
- 349
Zebrafish Whole-Adult-Organism Chemogenomics for Large-Scale Predictive and Discovery Chemical Biology
- Biology, Medicine
- PLoS genetics
- 2008
- 75
- PDF