Zanamivir in the prevention of influenza among healthy adults: a randomized controlled trial.

@article{Monto1999ZanamivirIT,
  title={Zanamivir in the prevention of influenza among healthy adults: a randomized controlled trial.},
  author={Arnold S. Monto and Dennis P. Robinson and M Louise Herlocher and John M. Hinson and Martin J. Elliott and Adam Crisp},
  journal={JAMA},
  year={1999},
  volume={282 1},
  pages={31-5}
}
CONTEXT The neuraminidase inhibitor zanamivir, a sialic acid analog administered directly to the respiratory tract, has been demonstrated in clinical studies to be effective in treatment of type A and B influenza. It has also been shown to prevent influenza infection and disease in an experimental model. OBJECTIVE To examine the efficacy of zanamivir, administered once daily, in the prevention of influenza infection and disease. DESIGN Double-blind, randomized, placebo-controlled trial… CONTINUE READING

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